Atix Hotel, a Member of Design Hotels  

In La Paz’s south (San Miguel / Macrodistrito Sur), this boutique luxury hotel sits in a shopping district just minutes from Megacenter Bolivia and the Japanese Garden. Handy for explorers — Cota Cota Park, Valle de la Luna, Arte al Aire Libre and the Irpavi cable car are all close by.

A concept-driven property that nods to Bolivian culture with contemporary design and local touches. There are 53 air-conditioned rooms with minibars, flat-screen TVs, laptop-compatible safes, and bathrooms fitted with rainfall showerheads and designer toiletries. Expect city views, a restorative spa vibe and clean, modern lines throughout.

Full-service spa offering massages, facials and body treatments, plus a sauna, steam bath, indoor pool and hot tub. Fitness center, massage room and concierge services keep you balanced and booked. Onsite parking and airport transfer options are available, and there’s a poolside bar and lounge for easy evening cocktails.

24-hour business center, express check-in and roughly 2,691 sq ft (250 m²) of conference and meeting space for events. Complimentary wired and wireless internet keeps work flowing.

Ona presents an avant-garde menu that celebrates Bolivia’s biodiversity, while Proyecto Nativa focuses on local flavors. +591 Bar serves creative cocktails with skyline views. There’s also a coffee shop/café, 24-hour room service and a complimentary buffet breakfast served each morning.