Holiday Inn Express Suites Amarillo South  

In south Amarillo just off I‑27, this Amarillo South hotel is a convenient stop for business and leisure. You're a short drive from Cadillac Ranch, Palo Duro Canyon State Park, the Panhandle‑Plains Historical Museum and the Amarillo Botanical Gardens, plus local shopping and dining along Historic Route 66. Nearby employers and medical centers include Bell Helicopter, Blue Cross Blue Shield, Owens Corning, Cactus Feeders, Texas Tech health campuses, the VA Medical Center and Northwest Texas Health Care System.

Set across 68 modern guestrooms, the property blends clean, contemporary décor with practical in‑room perks. Rooms commonly include microwaves, coffee/tea makers, irons and satellite TVs so you can recharge fast. Expect straightforward, upscale touches and friendly Texas hospitality without the fuss.

Take a dip in the indoor pool or unwind in the whirlpool/spa tub after a day exploring Palo Duro Canyon. Stay fit in the on‑site gym, plug into free high‑speed internet, and enjoy free self parking and elevator access. Laundry and dry‑cleaning services are available for longer stays.

Business‑friendly setups include a 24‑hour business center and a conference/meeting hall. Fast wired and wireless internet keeps you connected for work or virtual meetings.

A complimentary hot breakfast buffet is served daily to kickstart your morning. Rooms also offer coffee/tea makers for early departures, and a short drive brings you to classic Route 66 dining and local Amarillo restaurants.