Comfort Inn & Suites Greenville I-70  

In Greenville’s business district, minutes from Greenville Country Club and HSHS Holy Family Hospital. Close to Greenville College, the DeMoulin Museum, Patriot's Park and Copper Dock Winery. Pet-friendly and family-friendly hotel with St. Louis Lambert Intl roughly 60 miles away.

66 air-conditioned rooms with refrigerators, microwaves, LCD TVs, coffee makers and hair dryers. Private bathrooms have tubs or showers and complimentary toiletries; rooms include desks and free local calls. Practical, modern rooms plus accessible features, guest laundry and an elevator keep stays simple and comfortable. Pet policy: limit of 2 pets (up to 40 lb) per room; fees and refundable deposit apply.

Indoor heated pool, spa tub and a fitness center for staying active. Cozy lobby fireplace, free self-parking and guest laundry. Free Wi‑Fi throughout keeps you connected.

Business center, meeting room/conference hall and a 24-hour front desk. Free high-speed Wi‑Fi, ample parking and laundry facilities support work trips and events.

Complimentary hot buffet breakfast served daily from 6:00 AM to 9:00 AM, plus coffee and tea in the lobby. Fuel up here before heading out to local wineries or the golf course.