One Shot Prado  

In Madrid's lively city center, a boutique hotel just steps from Plaza de Santa Ana and a short walk to Puerta del Sol. Museums and culture are on your doorstep — Prado Museum (~0.3 mi), Thyssen-Bornemisza and Reina Sofía are all very close, and Gran Vía is about 0.5 km away.

Forty-two individually decorated rooms blend art-forward design with modern tech. Interiors by Las2Mercedes feature 42" Ad Notam Mirror TVs, touch-panel laptop-to-TV connections, iPod docks, minibars, safes and premium down-bedded memory foam options. Bathrooms boast 40 cm rainfall showers and designer toiletries; some rooms look over an interior courtyard.

Hit the city with concierge service, a 24-hour front desk and complimentary wireless internet access throughout. There are gift shops/newsstands, on-site paid parking and shuttle/transfer options to get you around. Wake up to true downtown mornings steps from tapas bars and museum-lined streets.

Express check-in and check-out, dry cleaning and laundry services, plus a conference hall and concierge support for tours and transfers. An airport shuttle and on-site self-parking are available (services may incur charges).

Grab a drink at the hotel bar or sit for local Spanish flavors in the on-site restaurant. Ask at check-in about breakfast options and neighborhood tapas recommendations.