Casa de Leda, a Kali Hotel  

In Santa Marta's Historic Center, steps from the Santa Marta Cathedral and a quick 3-minute walk to Parque de los Novios. Marina Santa Marta and the Customs House sit about 0.4 miles away, putting beaches, nightlife and historic sights within easy reach of this boutique spa hotel.

Housed in a restored late-19th-century mansion, Casa de Leda keeps original fluted columns, facade accents and floor tiling for a classic-meets-modern vibe. Rooms sit under vaulted ceilings with bright open bathrooms; many are individually decorated and some include in-room hot tubs, aromatherapy kits and flat-screen media players.

Full-service spa with massages and facials, indoor and outdoor pools, sauna and steam bath. An open terrace draped in vines overlooks the cathedral and uses a cooling mist system for warm afternoons. Tour desk, poolside lounging and an airport transfer (surcharge) make getting out and about effortless.

Complimentary wired and wireless internet throughout the property, concierge and a 24-hour front desk. Phones include free local calls and there are safe-deposit boxes and laundry services on site.

On-site restaurant and bar/lounge serve breakfast cooked-to-order and a menu for relaxed dinners. Room service is available during limited hours for low-key nights in.